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Mtisunge Banda has his expertise in human nutrition and the main passion is improving disease outcomes through clinical nutrition. Keen interest on Drug and diet interactions plus nutrient pathways during metabolism. Qualified to Masters of Science level in human nutrition and Bachelor’s level in nutrition and dietetics. Worked in both hospital and Community nutrition settings and conducted research in different districts in Malawi.
Statement of the Problem: Tuberculosis remains a considerable global public health concern with over nine million cases and 1.7 million deaths, costing billions of dollars yearly treating, management, high mortality, morbidity and loss of productivity. The nutritional consequences of active TB are well recognized by clinicians, yet little is known about effective nutritional management, nor of the interactions between TB treatment and nutritional status. Malawi has one of the highest TB burdens in the world with estimates 451/100,000 and the poor are most affected by the cost of TB, spending 244% of their monthly incomes. Therefore, this study aimed at conducting a trial in order to provide imperial evidence on the efficacy of supplements and/or combination in conjunction with standard TB treatment. Methodology & Theoretical Orientation: Randomized factorial design was used and patients were recruited at Bwaila and Queens referral hospitals. Patients were provided with multivitamin and/or high calorie and compared to the control group. Findings: A total of 81 patients were recruited, with 3.7% dropout rate. The mean age of was 35.8 ± 8 years and 80% were males. Mean BMI was 18.7 ± 2.3 and 41.6% classified malnourished. They were gradual increase in BMI to 20.9 kg/m2, presenting 11.8% with p= 0.041. The mean weight gain was 5.9kgs ± 4.3. Performance improvement was recorded with (t=-14.717, p <0.001) using Karnofsky index. Our findings show that the treatment success rate was 86%. The sputum conversion for supplemented was also significant for the supplemented over the controls at RR, 0.39 [95% CI, 0.17 to 0.86, p=0.03] at 2 months. Conclusion & Significance: we found beneficial factors existing of supplements on enhancing sputum conversion rates, treatment success rates, weight gain, improve quality of life, and reduce mortality. Nutritional supplements in tuberculosis patients are a feasible and have public health importance.